BALTIMORE -- Manager Dave Trembley isn't worried that Jeremy Guthrie's poor start on Wednesday night will have any ill effects on the rest of the right-hander's season.

Guthrie, who allowed a season-high seven runs (six earned) over a season-low 4 2/3 innings, said he was "embarrassed" by his performance in the Orioles' 8-3 loss to the Yankees, apologizing to both teammates and fans, after the game.

"Let me start by saying I'm embarrassed by the way the game started, I was embarrassed by the way the game finished," Guthrie said. "I'm apologetic to fans who pay to come and watch the Orioles and watch us lose, in this case, because of me. I'm apologetic to teammates for the inability to help them win a game in four starts. I'm apologetic to Jorge [Posada] if he is to miss any time [because of me] yanking a pitch and hitting him."

For his part, Yankees manager Joe Girardi made sure to note that he does not wish to begin a war of words with the Orioles, and he does not believe Guthrie has thrown at the Yankees intentionally. Of the 17 batters Guthrie has hit since the beginning of the 2008 season, nine have been Yankees.

"I'm sure he's frustrated with it, too, because the last thing you want to do is give free baserunners," Girardi said. "He's got outstanding stuff. I know he's trying as hard as he can. It seems like he puts his heart out there. We're frustrated by it because we lost a player."

On Thursday afternoon, the nameplate above Guthrie's locker was gone, as were most of his belongings, save for a few jerseys. Asked if he was trying to remove some clutter, he agreed that was part of it.

"I think he really wanted to get one under his belt [on Wednesday] night against the Yankees," Trembley said prior to Thursday's series finale. "It didn't happen for him, and I think he was disappointed. He felt responsible for it, and I told him today that he shouldn't feel that way. He's a guy with a lot of pride. He works real hard. I think he expects himself to be perfect all of the time. When he's not, he takes responsibility for that, and it bothers him."

While filming a MASN commercial earlier this season, Trembley saw Guthrie getting his running in despite a torrential downpour.

"The guy just prepares himself. He works, he cares," he said. "He's coming off a season that wasn't up to his standards."

Guthrie (0-3) is winless in five starts this year, but he has improved his numbers considerably from last season. He tossed four consecutive quality starts prior to Wednesday and -- most important -- limited opponents to just two homers before New York's Robinson Cano tagged one on Wednesday.

Guthrie, who led the American League in losses (17) and home runs allowed last season (35), has made a conscious effort to revert back to his 2008 and 2007 self.